Variations in the Anatomical Liver Volume and the Function Based on 99m Technitium-Mebrofinate SPECT-CT Scan and Its Relation to the Primary Indication for Resection

Introduction: 99m Technetium -Mebrofinate SPECT-CT scan is a pre-operative investigation useful in assessing the global, lobar and dynamic liver function. The study aimed at discordance function (scintigraphy) within given volume of remnant to assess if variation related primary indication for resection. Methods: All patients who underwent Tc-Mebrofenin unit since 2018 were included. Data processed on workstation (MultiModality; Hermes Medical Solutions) anatomical volumes, global assessed as scintigraphy well uptake. was collated from prospectively maintained database. Results: Seventy seven scans Three had prior second stage Median 685ml (range: 135-1906ml). uptake 13.19/min 4.66-27.4). Percentages vs. functional distribution shown Figure 1. There no 17/77 (22%), up 4.9% 31/77 (40%), 5-9.9% 12/77 (15.5%), more than 10% (22%). More 5% discordence noted 50% with cancers comparison 22% colorectal metastases (p=0.025). Conclusion: Distribution non-homogeneous significant cancers. or equivalent should be considered assessment undergoing major resections.